May 5, 2025 · Hereditary spastic paraplegia (HSP), also called familial spastic paraparesis, is a group of rare and progressive inherited disorders that cause weakness and stiffness of the legs (spasticity).

Aug 22, 2024 · Hereditary spastic paraplegia (pronounced “huh-RED-eh-ter-ee” “SPAS-ti”k “par-uh-PLEE-jee-uh”) is a group of inherited conditions that cause weakness and tightness (spasticity) in …

HSP is also known as hereditary spastic paraparesis, familial spastic paraplegia, French settlement disease, Strumpell disease, or Strumpell-Lorrain disease. The symptoms are a result of dysfunction …

Hereditary spastic paraplegia is a group of rare hereditary disorders characterized by progressive, spinal, nonsegmental spastic leg paresis, sometimes with intellectual disability, seizures, and other …

Oct 16, 2024 · Hereditary spastic paraplegia (HSP) is not a single disease entity; it is a group of clinically and genetically diverse disorders that share a primary feature, which is the causation of...

Hereditary spastic paraplegia is a general term for a group of rare inherited disorders that cause weakness and stiffness in the leg muscles. Symptoms gradually get worse over time. It's also known …

The hallmark of HSP is progressive difficulty walking due to increasingly weak and stiff (spastic) muscles. Symptoms appear in most people between the second and fourth decade of life, but they …

It is a condition of the upper motor neurons, which causes spasticity (muscle stiffness) and paraplegia (paralysis) of the lower limbs. Typically, those with HSP will have mobility issues caused by …

Hereditary spastic paraplegia (HSP), also called familial spastic paraparesis (FSP), refers to a group of inherited disorders that are characterized by progressive weakness and spasticity (stiffness) of the …

Hereditary spastic paraplegia (HSP) is a group of hereditary, degenerative, neurological disorders that primarily affect the upper motor neurons. Upper motor neurons in the brain and spinal cord deliver …