PIK3CA gene: MedlinePlus Genetics
The PIK3CA gene provides instructions for making the p110 alpha (p110α) protein, which is one piece (subunit) of an enzyme called phosphatidylinositol 3-kinase (PI3K). Learn about this …
P110α - Wikipedia
The phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (the HUGO -approved official symbol = PIK3CA; HGNC ID, HGNC:8975), also called p110α protein, is a class I PI 3 …
What Is The PIK3CA Mutation? Definition & Function
What Is PIK3CA? PIK3CA is a gene that gives your cells instructions for how to make a protein called p110 alpha. This protein is part of an enzyme called PI3K. PI3K helps control how your …
PIK3CA Gene - GeneCards | PK3CA Protein | PK3CA Antibody
Nov 14, 2025 · PIK3CA (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha) is a Protein Coding gene. Diseases associated with PIK3CA include Megalencephaly-Capillary …
The Effect and Treatment of PIK3CA Mutations in Breast Cancer: …
These findings suggest that PIK3CA mutations contribute to cell proliferation, apoptosis suppression, and tumorigenesis through the activation of the PI3K/AKT/mTOR pathway. This …
PIK3CA Mutation: What It Is and Why It Matters - Biology Insights
PIK3CA mutations appear in ovarian cancer and in head and neck squamous cell carcinoma. The presence of a PIK3CA mutation can influence cancer aggressiveness, prognosis, or resistance …
Prevalence and clinical implications of PIK3CA aberrations across ...
Sep 1, 2025 · Given the challenges of therapeutic approaches targeting PIK3CA aberrations, we analyzed the incidence of PIK3CA alterations, including amplification and fusions, in 3886 …
Definition of PIK3CA gene - NCI Dictionary of Cancer Terms
A gene that makes one of the proteins in an enzyme called PI3K, which is involved in many important functions in a cell. Mutations (changes) in the PIK3CA gene may cause the PI3K …
Oncogenic mutations of PIK3CA lead to increased membrane
Jan 12, 2023 · The PIK3CA gene is one of the most frequently mutated genes in all of human cancer.
PIK3CA Mutation - Know Your Biomarker
PIK3CA is a gene that encodes one piece (a subunit) of an enzyme called phosphatidylinositol 3-kinase. PIK3CA plays a role in the way cell growth, cell survival, and cell migration are controlled.