Cachexia (wasting syndrome) is a condition that causes significant weight loss and muscle loss. It often affects people who have cancer or heart failure.

In 2011, experts updated this definition, saying cachexia is "a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully …

Nov 17, 2025 · Cachexia is a wasting syndrome that comes with advanced cancers and other serious health conditions. When you have it, you will lose weight and muscle mass without trying.

Feb 4, 2025 · What is cachexia? Cachexia is a complex, hypercatabolic state that is driven by a chronic inflammatory response and is characterized by the progressive loss of skeletal muscle …

Dec 11, 2017 · Cachexia is a “wasting” disorder that causes extreme weight loss and muscle wasting, and can include loss of body fat. It typically occurs in the late stage of serious …

Cachexia is a multifactorial disease characterized by weight loss via skeletal muscle and adipose tissue loss, an imbalance in metabolic regulation, and reduced food intake.

A condition marked by a loss of more than 10% of body weight, including loss of muscle mass and fat, in a person who is not trying to lose weight. Some people with cachexia may also have …