After a well-rested bye week, the no. 25 Houston Cougars begin their final stretch of the season as they take on the TCU Horned Frogs in the last home game of t

The TCU Horned Frogs (6-4, 3-4 Big 12) and Houston Cougars (8-2, 5-2) tangle in Big 12 action Saturday. The contest at TDECU Stadium in Houston, Texas, will kick off at 4 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NCAA football odds around the TCU at Houston odds and make our expert college football picks and predictions for the best bets.

The Cougars are still in the Big 12 title chase, but the Horned Frogs are looking to screw that up. Here's the TCU vs Houston preview and prediction.

Houston football hosts the TCU Horned Frogs on Saturday, Nov. 22, at 3 p.m., inside TDECU Stadium, in Houston, Texas. The Cougars are 8-2 on the season, and the

College football Week 13 odds, picks, predictions, TV channel, streaming for TCU Horned Frogs vs Houston Cougars game on Saturday, Nov. 22, 2025.

Josh Hoover connected with Jordan Dwyer for a 17-yard TD to extend the TCU Horned Frogs' lead over the No. 23 Houston Cougars.

Josh Hoover found Eric McAlister for 33-yard TD to give the TCU Horned Frogs the lead over the #23 Houston Cougars.