White matter hyperintensities and reduced cerebral blood flow are hallmarks of cerebral small vessel disease (CSVD). We tested the feasibility of daily treatment with the vasoactive drug tadalafil in ...
Background This multicenter, randomized, double-blind, double-dummy, placebo-controlled trial primarily evaluated the efficacy of tadalafil once-daily (OaD) or on-demand ("pro-re-nata"; PRN) treatment ...
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Neoadjuvant serplulimab in combination with concurrent chemoradiotherapy for locally advanced, resectable esophagogastric junction adenocarcinoma. Impact of immunotherapy combined with neoadjuvant ...
Opsynvi is a combination of macitentan, an endothelin receptor antagonist, and tadalafil, a phosphodiesterase 5 inhibitor. The Food and Drug Administration (FDA) has approved Opsynvi ® (macitentan and ...
New Delhi: Granting approval for Phase III clinical trial and bioequivalence (BE) study wavier, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organization ...
aDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SU Sahlgrenska, 413 45 Gothenburg, Sweden bDepartment of Neuroscience and ...
Tadalafil (Amore 20mg) is a phosphodiesterase (PDE) inhibitor, prescribed for erectile dysfunction (impotence; inability to get or keep an erection) in men. It increases blood flow to the penis during ...