Conan O'Brien's wife, Liza Powel O'Brien, was by his side when he received the Mark Twain Award for American Humor. "I immediately start talking to her [Liza], and then I'm not even trying to be funny ...

The Oscars host is also a husband and father of two. Longtime comedian Conan O'Brien wears many hats and chief among them is that of a proud father of two children, whom he shares with his wife, Liza.

Look who’s in town today. Conan O’Brien, host of Conan on TBS, was spotted at the Cactus Restaurant in Seattle with his wife Liza (a Seattle native) this afternoon. Former Seattle City Councilmember ...

Liza Powel O’Brien cheered Conan O'Brien on as he accepted the Mark Twain prize for American Humor in 2025 Conan O'Brien's wife, Liza Powel O'Brien, was by his side when he received the Mark Twain ...