In Sporting News' Week 16 picks against the spread, Detroit and Green Bay rebound from tough losses while the Chargers, ...

The NFL playoff race is heating up, and these two former Stanford Cardinal helped propel their teams to victory on Sunday.

Despite losing to the Seattle Seahawks on Sunday in his first start since the 2020 season, Indianapolis Colts veteran ...

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Monday Night Football between San Francisco 49ers and Indianapolis Colts.

Here is the injury update for the Indianapolis Colts and San Francisco 49ers entering their Week 16 matchup.

How do all 32 teams in the NFL stack up against each other coming out of Week 15 of the 2025 NFL regular season? Here's an ...

The 49ers face the Titans at home in Santa Clara in Week 15. We break down what the game means for the NFL playoff picture.

The NFL season continues in Week 15 when the San Francisco 49ers host the Tennessee Titans on Sunday. Start time, how to ...

SANTA CLARA, Calif. (AP) — San Francisco coach Kyle Shanahan heard plenty during the bye week from friends and family about the prime position the 49ers are in entering the stretch run of the season.

USA Today's NFL experts make their picks for a Week 15 showdown between the San Francisco 49ers and Tennessee Titans ...

Brock Purdy threw a one-yard TD to George Kittle that extended the San Francisco 49ers lead to 31-10 over the Tennessee ...

Cam Ward threw a 34-yard TD to Gunnar Helm that trimmed the Tennessee Titans deficit to 14-10 against the San Francisco 49ers.