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Clinical Development of ETX101, a Gene Regulation Therapy for SCN1A+ Dravet Syndrome

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Demographics, Prevalence, and Characteristics of Limbal Stem Cell Deficiency in Southern California.

Limbal stem cell deficiency (LSCD) is a potentially blinding disease characterized by the loss of the stem cell population. The purpose of this publication is to report the prevalence, incidence and ...
cirm.ca.gov

Androgenetic alopecia.

Yingzi Liu, Antonella Tosti, Etienne C E Wang, Stefanie Heilmann-Heimbach, Crystal Aguh, Francisco Jimenez, Sung-Jan Lin, Ohsang Kwon, Maksim V Plikus Androgenetic alopecia (AGA) is a condition of ...
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Effects of PDMS culture on stem cell differentiation towards definitive endoderm and hepatocytes.

Keywords: Induced pluripotent stem cells; Liver tissue engineering; Mechanosensing; PDMS; Substrate stiffness. The generation of human induced pluripotent stem cell (hiPSC) derivatives for ...
cirm.ca.gov

Complementary biomolecular coassemblies direct energy transport for cardiac photostimulators.

Ze-Fan Yao, Sujeung Lim, Yuyao Kuang, Emil M Lundqvist, Natalie Celt, Caleb O Chung, Kathryn K Lee, Krystal Nguyen, Lanie Le, Sheng Wei Tang, Griffin M Milligan, Phillip Kohl, Tarunya Rao Sudarshan, ...
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Funding Opportunities

At the California Institute for Regenerative Medicine (CIRM), we are committed to the continued funding of groundbreaking research in regenerative medicine. To reflect this commitment, we are ...
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干细胞生物学和再生医学研究培训计划

癌症治疗仍然十分困难，因为肿瘤细胞能够躲避免疫系统的攻击，而且其表达的标志物也常常存在差异。在这个项目中，我们开发了一种新型的工程化免疫细胞——CAR-巨噬细胞，它既能识别癌 ...
cirm.ca.gov

碳纳米材料及其聚合物复合材料在神经组织工程中的应用进展。

碳基纳米材料（CBMs）及其聚合物复合材料在治疗神经创伤和神经退行性疾病方面引起了广泛关注，因为修复受损的中枢和周围神经系统仍然是临床上面临的一项持续挑战。这些材料具有优异的 ...
cirm.ca.gov

CIRM学者综合研究培训计划

Keywords: biomaterials; cardiac tissue engineering; patterning; peptides; photoconductive materials. The propagation of electrical signals in the human heart relies on organized conduction pathways to ...
cirm.ca.gov

CIRM学者综合研究培训计划

Keywords: Tn antigen; bispecific; glycan-dependent T cell recruiter; immunosuppression; immunotherapy; pan-cancer; siayl-Tn antigen; tumor microenvironment; tumor-associated carbohydrate antigens; ...
cirm.ca.gov

CIRM学者综合研究培训计划

PIEZO1 is critical to numerous physiological processes, transducing diverse mechanical stimuli into electrical and chemical signals. Recent studies underscore the importance of visualizing endogenous ...
cirm.ca.gov

An experimental census of retrons for DNA production and genome editing.

Retrons are bacterial immune systems that use reverse transcribed DNA as a detector of phage infection. They are also increasingly deployed as a component of biotechnology. For genome editing, for ...