Nura Bio raised $73.8 million to advance two experimental SARM1 inhibitors. The therapies are designed to block SARM1, a ...

When a parent develops amyotrophic lateral sclerosis (ALS), adult children may face heavy emotional pressures and may have ...

ALS and other motor neuron diseases are increasing in Europe, with a 2.8% annual prevalence rise. This rise is partly due to ...

The event sprang from a simple truth: ALS patients and caregivers frequently encounter ironic, absurd, and humorous situations when the so-called real world meets ALS. With this event, we wanted to ...

It’s stressful to always be on duty, ready to move an arm, scratch an itch, make micro adjustments to his noninvasive ventilation nasal pillows, or help clear his lungs when they fill with mucus. The ...

TRCN-1023, an experimental treatment for ALS, aims to restore UNC13A function. It is designed to improve communication between nerves and muscles. Global Phase 1/2 clinical trials are underway to ...

Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease that results in the death of nerve cells called motor neurons in the brain and spinal cord. These neurons control voluntary ...

AMX0114, an investigational therapy for ALS, showed safety and good tolerability at its lowest dose in a first-in-human clinical trial. Developer Amylyx is now advancing that trial, called LUMINA, to ...

A clinical trial in Europe is testing the safety and pharmacological properties of LTX-002 as a potential treatment for ALS. The new therapy targets dysregulated fat metabolism, a key contributor to ...

A couple months ago, I planted zinnia and strawflower seeds in two plastic bins and set them in the sunlight under our patio window in my dining room. I’ve grown vegetables from seeds in the past, but ...

Lower adiponectin and IL-10 levels are linked to faster ALS progression and shorter survival. These molecules may serve as biomarkers for ALS prognosis and guide new treatment development. Initial ...