George Clooney is remembering the role that made him famous. Clooney's role as the hunky Dr. Doug Ross in the medical drama catapulted him to stardom — and solidified his Hollywood heartthrob status. He would go on to launch a prolific film career.

George Clooney will never forget that he lost a role in “Thelma & Louise” to Brad Pitt. “I got to the final test for a role in ‘Thelma & Louise.’ And, motherf—er, Brad got it,” Clooney, 64, said about his “Ocean’s Eleven” co-star, 61, in a new interview with The Times UK.

George Clooney made a name for himself with ER, but before that, he performed low-key foot operations.During George’s recent appearance on Live With Kelly and Mark, the Jay Kelly star

Jay Kelly' star George Clooney shared a gross story about regularly handling old ladies' foot corns before he made it big as a Hollywood actor.

ER ‘s memorable, outstanding “Hell and High Water,” which aired 30 years ago (November 9, 1995), is one of them. Doug Ross (George Clooney), just as he’s about to leave the hospital for a job in a private practice, ends up in the middle of a high-stakes rescue during a storm: saving a boy (Erik von Detten) who’s trapped in a storm drain.

George Clooney led a parade of old favorites back to "ER" on Thursday as the medical drama nears the end of its 15-year run. Clooney, who left the show in 1999 to pursue movie stardom, reprised his character Dr. Doug Ross. Now in Seattle, Ross works with ...

In ‘Jay Kelly,’ he plays the last of the old-school leading men. It's a persona he's embodied on and off screen for three decades—even while subverting his own stardom at every turn.

According to IMDb users, Ocean's Eleven, Fantastic Mr. Fox, and O Brother, Where Art Thou? are among the best movies starring George Clooney.

George Clooney slams celebrity diva behavior on sets, sharing how his Kentucky farm upbringing keeps him grounded in Hollywood's ego-driven culture.