Malignant hyperthermia is a potential side effect or complication that may arise in patients who have received general anesthesia. This adverse event typically occurs during surgery and other invasive ...

Malignant hyperthermia (MH) is a life‐threatening pharmacogenetic disorder of skeletal muscle characterised by a hypermetabolic response to certain anaesthetic agents. Research in this field has ...

“Uncle Joe woke up from minor surgery packed in ice.” That’s more than interesting family gossip. It’s an ominous clue that Joe’s relatives are at risk for a rare, inherited condition that can make ...

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and ...

Early in the course of the development of these agents, haloperidol was found to cause not only hypokinetic and hyperkinetic motor disorders but also a potentially fatal syndrome of muscle rigidity ...