The underlying mechanism is well known: put simply, synaptic signal transmission is triggered when calcium ions in the sender neuron bind to specific sensor proteins, which causes messengers—known as ...

Researchers at VIB-KU Leuven shed light on an unusual signaling pathway that orchestrates synaptic structure and function during brain development. Leuven, 20 May 2025 - Researchers from the lab led ...

Low-dose ephedrine disrupts synaptic signaling and behavior in adult zebrafish. Schematic overview of the experimental design, key neurotoxic mechanisms, and functional outcomes following chronic ...

One of society’s greatest medical challenges is to understand and develop effective treatments for disorders of intellectual disability (ID). Around 2–3 percent of the global population meet the ...

Transcriptomic analyses revealed thousands of differentially expressed genes in the brain, with synaptogenesis signaling emerging as the most significantly disrupted pathway—even at the lowest ...