Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Researchers at the University of Illinois at Urbana-Champaign have shown for the first time that expensive aberration-corrected microscopes are no longer required to achieve record-breaking ...

When designing microscopes, optical engineers have long faced a trade-off between speed, field of view and resolution. But improving one of these properties typically comes at the expense of another.

Electron microscopes are used wherever particularly small details need to be imaged. But from a strictly physical point of ...

A new computational microscopy technique solves for true high-resolution images without the guesswork that has limited the precision of other techniques. For hundreds of years, the clarity and ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

Microscopes have long been scientists' eyes into the unseen, revealing everything from bustling cells to viruses and nanoscale structures. However, even the most powerful optical microscopes have been ...

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue ...

Cancer drugs are often designed to block specific molecular targets, but what happens after they enter a cell is not always ...

Advanced light microscopy techniques are giving scientists a new understanding of human biology and what goes wrong in diseases Katarina Zimmer, Knowable Magazine Key takeaways: Super-resolution ...