Single-stranded DNA-binding proteins (SSBs) are central guardians of genome integrity, selectively coating exposed single-stranded DNA (ssDNA) intermediates that arise during replication, ...
CAMBRIDGE, Mass., March 11, 2026 /PRNewswire/ -- Full Circles Therapeutics today announced that its circular single-stranded DNA (cssDNA, C4DNA™) technology platform has been highlighted as a key ...
To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...
Figure 1. Design and synthesis of circAMO . (a) Synthesis of a single-molecule ring by rigid regulation of selectivity; (b) Schematic diagram of circAMO design; (c) Synthesis of circAMO; (d) ...
Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with ...
Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...
Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 ...
A study revealed that EXO1 overexpression causes DNA instability in tumors, creating vulnerabilities similar to BRCA-mutant ...
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