The US Food and Drug Administration has approved the Sapien M3 system for transseptal transcatheter mitral valve replacement (TMVR) for use in patients with symptomatic moderate-to-severe mitral ...

The Sapien M3 device is the first approved mitral regurgitation treatment to use a transseptal approach, Edwards said.

Mitral valve regurgitation is a heart condition that occurs when the mitral valve does not close properly, allowing blood to flow backward into the left atrium. Symptoms do not always occur. When they ...

A new study, published by Kazem Rahimi of The George Institute for Global Health at the University of Oxford, UK and colleagues, indicates that high blood pressure increases the risk of mitral ...