Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Hepatorenal syndrome (HRS) is a severe complication of advanced liver disease with high mortality and limited treatment options, often requiring liver or combined liver-kidney transplantation. Current ...

A new study from the University of Oklahoma reveals how a little-understood protein, CD82, contributes to blood vessel leakage, a process that initiates inflammation but becomes dangerous when it ...

Innate and adaptive immune cells coordinate the excessive inflammatory response known as a cytokine storm in acute respiratory distress syndrome, leading to alveolar–capillary barrier damage, ...