Animal models have long shaped how biomedical research is conducted. They have influenced how diseases are studied, how ...
For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...
A frequently reported fact in the drug discovery and development industry is that approximately 90 % of drug candidates reaching clinical trials fail, with even higher amounts discarded before ...
Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...