Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid ...
The monoclonal antibody Herceptin drastically improves prognosis for patients with HER2+ breast cancer. But if the primary tumor metastasizes to the brain, it often fails to respond to treatments.
A working model showing that CAFs exhibit profound amino acid reprogramming, especially the production of glycine, in CRC. CRC cell‐derived TGF‐β1 activates de novo glycine synthesis in CAFs, ...
This study is led by Prof. Dr. Shengying Li (State Key Laboratory of Microbial Technology, Shandong University) and Ass. Prof. Dr. Biaobiao Zhang (School of Science, Westlake University). The team ...
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