The centrosome is a small, non-membrane-bound organelle endowed with the remarkable capacity to nucleate and organize microtubules. It consists of a pair of centrioles — structures analogous to the ...
Centrosomes, which are composed of two centrioles and pericentriolar material, serve as the main microtubule-organizing centre in animal cells. They duplicate once per cell cycle so that each daughter ...
Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...
The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that ...
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8+ T cell division for the generation of memory precursor cells.