Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...
Human artificial chromosomes (HACs) could be useful tools for both understanding how mammalian chromosomes function and creating synthetic biological systems, but for the last 20 years, they have been ...
This release is available in German. Centromeres are specialised regions of the genome, which can be identified under the microscope as the primary constriction in X-shaped chromosomes. The cell ...
Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ...
Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply—and can contribute to ...
About a third to two-thirds down the shaft of a chromosome is a constricted site called the centromere. When a chromosome replicates, the old and new pair (called chromatids) are held together at this ...
Just like you might use a belt to keep your clothes in place, the centromere holds a pair of chromatids together and attaches it to the mitotic spindle during cell division to ensure that each ...
• The parasitic genus Cuscuta (Convolvulaceae) is exceptional among plants with respect to centromere organization, including both monocentric and holocentric chromosomes, and substantial variation in ...
Human chromosomes contain a distinct centromeric domain, which encompasses a block of highly repetitive alpha satellite DNA, and it is characterised by a specific chromatin signature and associated ...
O. Delattre, A. Bernard, B. Malfoy, F. Marlhens, E. Viegas-Pequignot, C. Brossard, O. Haguenauer, N. Creau-Goldberg, N'Guyen Van Cong, B. Dutrillaux and G. Thomas ...
Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...