Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue.

Despite advancements in diagnostic and therapeutic strategies, hepatocellular carcinoma (HCC) remains a leading cause of ...

Alcohol-associated liver disease (ALD) is a major cause of liver transplantation and death worldwide, and its impact is only ...

Activation of cell death pathways typically leads to the irreversible destruction of the cell. However, in this issue of The ...

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Psychiatric disorders, including depression, schizophrenia, anxiety, and bipolar disorder, are increasingly recognized as ...

A study published in PNAS has found that for people with a rare form of ichthyosis, medications previously used to treat ...

Another area of research is the use of PIK3CA inhibitors which block the activity of phosphatidylinositol 3-kinase alpha (PI3Kα) a key player in cell signaling pathway that promote cancer cell ...

Signalling pathways are used to transmit information within cells. These complex networks of molecules control critical cellular functions such as growth, division, cell death and, indeed, mitophagy.