Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue.

Thousands of previously “invisible” microproteins—tiny chains of fewer than 100 amino acids—can profoundly change human ...

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and ...

Single-cell analyses revealed molecular profiles that can distinguish PTSD from depression, potentially leading to better ...

A study published in PNAS has found that for people with a rare form of ichthyosis, medications previously used to treat ...

Bioelectrosynthesis platform enables switch-like, precision control of cell signaling by The Korea Advanced Institute of Science and Technology (KAIST) edited by Lisa Lock, reviewed by Robert Egan ...

Lower levels of natural lithium may increase amyloid plaques in brain regions vulnerable to Alzheimer’s — while a novel ...

Researchers at Weill Cornell Medicine report that a rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells in a preclinical ...

MAP4K4 ordinarily regulates cell movement and blood vessel growth. The researchers suggest the gene may thus also be responsible for the pathological angiogenesis of AVMs.

Beyond classic stress signaling: How mitochondrial stress softens the cell nucleus and alters cellular identity by Anna Euteneuer, University of Cologne edited by Sadie Harley, reviewed by Robert Egan ...