It's tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate ...
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
Single-cell analysis helps uncover how the BK virus replicates, opening the door to new drug targets. BK polyomavirus (BKPyV) is a major cause of kidney transplant failure. Without a complete ...
Researchers at Umeå University show how tick-borne viruses remodel human cells into virus factories, using an advanced microscopy method. The findings provide new insight into how the virus replicates ...
Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell survival if left unchecked. Cells control these "jumping genes" by ...
A new study revealed how cells defend themselves against jumping genes using RNA interference, and heterochromatin-based ...
Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme—RNase H2—that helps triple-negative breast cancer (TNBC) cells survive high levels of DNA replication ...