BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...

The presence of valve calcification increases the odds of at least mild paravalvular regurgitation after transcatheter aortic valve replacement (TAVR), according to a study published in the August ...

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

Lipoprotein(a) is not associated with active calcification of the aortic valve in patients with mild-to-moderate aortic stenosis, according to a study presented this week at the European ...

New evidence shows regular aspirin use is associated with a lower incidence of aortic valve calcification and aortic stenosis ...

(CHICAGO) –Bone-like cells similar to the cells found in the skeleton calcify in the heart's aortic valve and are responsible for the blockages that lead to the need for open-heart surgery to replace ...

Aortic valve disease encompasses a spectrum of disorders affecting the aortic valve, with calcification being a hallmark of the most severe forms. Calcific aortic valve disease (CAVD) is characterised ...

Calcific aortic stenosis in the elderly is the number one cause of surgical valve replacement in the US and Europe. The incidence of calcific aortic stenosis is increasing as the general age of the ...

The human body has sophisticated defenses against the deposition of calcium minerals that stiffen heart tissues, researchers at the University of Illinois Urbana-Champaign and collaborators at UCLA ...

Leaflet calcification and hemodynamic valve deterioration (HVD) of surgically implanted bioprosthetic aortic valves are independently associated with a major increase in death or valve reintervention, ...

We determined genomewide associations with the presence of aortic-valve calcification (among 6942 participants) and mitral annular calcification (among 3795 participants), as detected by computed ...

THE transventricular and transaortic approaches, with visualization of the valve, to correct calcareous aortic stenosis were logical and progressive strides in the development of the surgical ...