The NFL's upcoming lineup of games is rife with questions. But there's little question that the Chiefs are approaching must-win territory in Week 12.

I’m back with my straight-up picks with confidence levels. I had a nice bounce-back performance last week, finishing 12-3 overall. I was 3-0 with my high confidence picks, 3-1 with my medium confidence picks, and 6-2 with my low confidence picks.

It’s Week 12! A few teams have placed themselves firmly in the playoff picture, while a few players are separating themselves in the MVP race. One player we won’t see this week is Ja’Marr Chase (though Conor Orr says players shouldn’t be suspended for spitting ).

Some of the site's predictions differ from NFL Week 12 odds and other NFL Week 12 picks for NFL Week 12 games. How correct will the analytics be this week? Click on each game for more NFL Week 12 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.

You've seen the model's best bets for Indianapolis Colts vs. Kansas City Chiefs. Now, get against the spread, total and money-line picks for every Week 12 NFL game here, all from the model that's simulated every game 10,000 times.

Brent Sobleski, Gary Davenport, Kris Knox and Moe Moton—will highlight each contest's biggest takeaways, as well as the latest winners and losers, throughout the weekend. Score: Texans 23, Bills 19 Texans Takeaway: Full Speed Ahead Toward Top of AFC South The Indianapolis Colts may be the best story in the NFL,